880 research outputs found

    Additive Pattern Database Heuristics

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    We explore a method for computing admissible heuristic evaluation functions for search problems. It utilizes pattern databases, which are precomputed tables of the exact cost of solving various subproblems of an existing problem. Unlike standard pattern database heuristics, however, we partition our problems into disjoint subproblems, so that the costs of solving the different subproblems can be added together without overestimating the cost of solving the original problem. Previously, we showed how to statically partition the sliding-tile puzzles into disjoint groups of tiles to compute an admissible heuristic, using the same partition for each state and problem instance. Here we extend the method and show that it applies to other domains as well. We also present another method for additive heuristics which we call dynamically partitioned pattern databases. Here we partition the problem into disjoint subproblems for each state of the search dynamically. We discuss the pros and cons of each of these methods and apply both methods to three different problem domains: the sliding-tile puzzles, the 4-peg Towers of Hanoi problem, and finding an optimal vertex cover of a graph. We find that in some problem domains, static partitioning is most effective, while in others dynamic partitioning is a better choice. In each of these problem domains, either statically partitioned or dynamically partitioned pattern database heuristics are the best known heuristics for the problem

    Phase Transition in the Number Partitioning Problem

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    Number partitioning is an NP-complete problem of combinatorial optimization. A statistical mechanics analysis reveals the existence of a phase transition that separates the easy from the hard to solve instances and that reflects the pseudo-polynomiality of number partitioning. The phase diagram and the value of the typical ground state energy are calculated.Comment: minor changes (references, typos and discussion of results

    Random Costs in Combinatorial Optimization

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    The random cost problem is the problem of finding the minimum in an exponentially long list of random numbers. By definition, this problem cannot be solved faster than by exhaustive search. It is shown that a classical NP-hard optimization problem, number partitioning, is essentially equivalent to the random cost problem. This explains the bad performance of heuristic approaches to the number partitioning problem and allows us to calculate the probability distributions of the optimum and sub-optimum costs.Comment: 4 pages, Revtex, 2 figures (eps), submitted to PR

    Optimal combinations of imperfect objects

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    We address the question of how to make best use of imperfect objects, such as defective analog and digital components. We show that perfect, or near-perfect, devices can be constructed by taking combinations of such defects. Any remaining objects can be recycled efficiently. In addition to its practical applications, our `defect combination problem' provides a novel generalization of classical optimization problems.Comment: 4 pages, 3 figures, minor change

    Phase Transition in Multiprocessor Scheduling

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    The problem of distributing the workload on a parallel computer to minimize the overall runtime is known as Multiprocessor Scheduling Problem. It is NP-hard, but like many other NP-hard problems, the average hardness of random instances displays an ``easy-hard'' phase transition. The transition in Multiprocessor Scheduling can be analyzed using elementary notions from crystallography (Bravais lattices) and statistical mechanics (Potts vectors). The analysis reveals the control parameter of the transition and its critical value including finite size corrections. The transition is identified in the performance of practical scheduling algorithms.Comment: 6 pages, revtex

    Entropy-based analysis of the number partitioning problem

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    In this paper we apply the multicanonical method of statistical physics on the number-partitioning problem (NPP). This problem is a basic NP-hard problem from computer science, and can be formulated as a spin-glass problem. We compute the spectral degeneracy, which gives us information about the number of solutions for a given cost EE and cardinality mm. We also study an extension of this problem for QQ partitions. We show that a fundamental difference on the spectral degeneracy of the generalized (Q>2Q>2) NPP exists, which could explain why it is so difficult to find good solutions for this case. The information obtained with the multicanonical method can be very useful on the construction of new algorithms.Comment: 6 pages, 4 figure

    Statins, bone, and neurofibromatosis type 1

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    Neurofibromatosis type 1 (NF1) is a dominantly inherited multi-system disorder. Major features include pigmentary abnormalities, benign tumors of the nerve sheath (neurofibromas), malignant tumors, learning disabilities, and skeletal dysplasia. The NF1 gene functions as a tumor suppressor, but haploinsuffiency probably accounts for some aspects of the non-tumor phenotype. The protein product, neurofibromin, is a Ras GTPase-activating protein, and various Ras pathway inhibitors are being tested in preclinical models and clinical trials for effectiveness in treating NF1 complications. This month in BMC Medicine, a paper by Kolanczyk et al describes a preclinical mouse model for tibial dysplasia and provides evidence that the drug lovastatin – in use to treat cardiovascular disease – may be beneficial, opening the door to clinical trials in humans
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